Glutathione S Transferase

Glutathione S Transferase

Glutathione S Transferase (GST) is a vital enzyme, that is separate from glutathione (GSH), the master antioxidant (and the main subject of this website).

GST and GSH work together in harmony to detoxify!

Glutathione S Transferase (GST) is an enzyme that aids in detoxification. GST does this by speeding up the linking of toxic compounds with glutathione (GSH), thus forming a less reactive substance.(1)

Glutathione S-transferases are a "family" of enzymes of AT LEAST NINE independent members known as:

Alpha (GSTA)
Kappa (GSTK)
Mu (GSTM)
Pi (GSTP)
Sigma(GSTS)
Theta(GSTT)
Zeta (GSTZ)
Omega (GSTO)
Microsomal (MGST)
Wow! and more being discovered!

The family of Glutathione s-transferases (GSTs) make up the most vital enzymes that protect:

-humans from toxic chemicals, pesticides, herbicides, carcinogens, drugs, and many other harmful pathogens

-plants from pesticides, herbicides, insects, pathogens, and other chemical compounds that are harmful to their survival.

-and many other organisms from insecticides, pesticides, herbicides, and many other chemicals

Even tiny organisms, such as bed bugs are protected from chemical bug sprays!

In addition, GSTs may help in transporting non-water soluble compounds (hydrophobic compounds) such as certain salts, within the cells.

Turmeric, a spice which contains curcumin, has been found to contain GST, thus is being studied for its anti-inflammatory, antioxidant, and anti-tumor properties.(2)

Eating a healthy diet full of raw foods, fruits, vegetables, proteins, and even herbs and spices, along with keeping your glutathione (GSH) levels high, all help keep your Glutathione S-Tranferase enzymes functioning optimally.

Sources:

(1)Glutathione S-transferase: an enzyme for chemical defense in plants Brazilian Agricultural Research

(2)Multiple Molecular Targets in Cancer Chemoprevention by Curcumin
The aaps journal published study

The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance Study on PubMed

GST's on Wikipedia

On Amazon (a thorough book on GST's):
Glutathione S-Transferases: Structure, Function and Clinical Implications


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